Monitoring Blood Burble and Increasing Longevity of Prosthetic Heart Valves

In an international joint project, scientists are now testing prosthetic pumping systems, in which coatings increase the longevity of heart valves. At the same time, they are able to monitor the heart valve. The project "HeartSen" is led by the INM – Leibniz Institute for New Materials.

The prosthetic heart valves are tested in a pumping system outside the human body. In these systems, human blood or blood substitutes are running around in circles. The two overlapping coatings on the heart valves fulfill various purposes: "At first, we apply a magnetic layer", says Cenk Aktas, the head of the program division "CVD/Biosurfaces" at INM – Leibniz Institute for New Materials. "A sensor which is outside the heart valve transmits the signals of this magnetic layer. Depending on how well the blood flows through, we receive different signals, which give us information about the valves function", continues the project leader. The second layer works as protective layer to prevent the deposition of blood components. "By combining these two layers, we can precisely design the protective layer to optimize longevity of the heart valve ", says the materials scientist Aktas.

The prosthetic valves consist of titan. Both layers are applied one after another. Similar to hot water vapor on the pot lid, the materials precipitate on the titan valve in a very thin, uniform layer. The protective layer consists of adamantine carbon. With a thickness of 100 to 150 nm (millionths of a millimeter), the artificial system is comparable to prosthetic heart valves.

In the joint project "HeartSean", scientists from four institutions are working together: INM – Leibniz Institute for New Materials, Saarbrücken/Germany, the Pediatric Cardiology of Saarland University Hospital, Homburg/Germany, and Indian Institute of Technology Madras as well as Kocaeli University, Turkey. The project started in July 2011 under the leadership of INM. "HeartSen" is part of the project "New Indigo", a cooperation between Europe and India. This cooperation stems from the Seventh Framework Programme FP7, which bundles all research-related EU initiatives together under a common roof, the initiatives playing a central role in reaching the goals of growth, competitiveness, and employment.; Source: The National Science Foundation