Manufacturers Trader OEM

Demeditec Diagnostics GmbH

Lise-Meitner-Str. 2 , 24145 Kiel
Germany

Telephone +49 431 71922-0
Fax +49 431 71922-55
info@demeditec.de

Trade fair hall

  • Hall 3 / K65
 Interactive Plan

Hall map

MEDICA 2016 hall map (Hall 3): stand K65

Fairground map

MEDICA 2016 fairground map: Hall 3

Our range of products

Product categories

  • 03  Diagnostics
  • 03.01  Clinical chemistry
  • 03.01.14  Rapid tests - clinical chemistry

Rapid tests - clinical chemistry

  • 03  Diagnostics
  • 03.01  Clinical chemistry
  • 03.01.14  Rapid tests - clinical chemistry
  • 03.01.14.01  Point of care - testing systems

Point of care - testing systems

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.02  Anemia related / Vitamin tests

Anemia related / Vitamin tests

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.02  Anemia related / Vitamin tests
  • 03.02.02.01  Diagnostic agents / kits for vitamin determination

Diagnostic agents / kits for vitamin determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.03  Auto-immune diseases
  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.03  Auto-immune diseases
  • 03.02.03.01  Diagnostics / kits for the diabetes analyses

Diagnostics / kits for the diabetes analyses

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.03  Auto-immune diseases
  • 03.02.03.02  Diagnostics / kits for the gastro enterology

Diagnostics / kits for the gastro enterology

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.03  Auto-immune diseases
  • 03.02.03.03  Diagnostics / kits for the thyroid gland analyses (Auto-immune diseases)

Diagnostics / kits for the thyroid gland analyses (Auto-immune diseases)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.04  Fertility / Pregnancy hormones / Proteins

Fertility / Pregnancy hormones / Proteins

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.05  Units and systems for hormone determination

Units and systems for hormone determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.05  Units and systems for hormone determination
  • 03.02.05.01  Diagnostic agents / kits for hormone determination

Diagnostic agents / kits for hormone determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.05  Units and systems for hormone determination
  • 03.02.05.03  Control material for hormone determination

Control material for hormone determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.05  Units and systems for hormone determination
  • 03.02.05.04  Reagents for hormone determination

Reagents for hormone determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.05  Units and systems for hormone determination
  • 03.02.05.05  Accessories for hormone determination

Accessories for hormone determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones

Thyroid function hormones

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones
  • 03.02.06.01  Diagnostic agents / kits for thyroid gland, etc. determination (Thyroid function hormones)

Diagnostic agents / kits for thyroid gland, etc. determination (Thyroid function hormones)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones
  • 03.02.06.02  Units and systems for the determination of thyroid glands hormones

Units and systems for the determination of thyroid glands hormones

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones
  • 03.02.06.03  Control material for thyroid gland diagnostics

Control material for thyroid gland diagnostics

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones
  • 03.02.06.04  Reagents for thyroid gland diagnostics

Reagents for thyroid gland diagnostics

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.06  Thyroid function hormones
  • 03.02.06.05  Accessories for thyroid gland diagnostics

Accessories for thyroid gland diagnostics

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems

Immuno assay systems

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.02  Automatic radioimmunoassay

Automatic radioimmunoassay

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.03  Biogene amines

Biogene amines

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.06  Enzyme immunoassay (EIA, ELISA, EMIT)

Enzyme immunoassay (EIA, ELISA, EMIT)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.10  Heterogenous enzyme immunoassay

Heterogenous enzyme immunoassay

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.11  Homogenous enzyme immunoassay

Homogenous enzyme immunoassay

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.14  Immunoradiometric assay (IRMA)

Immunoradiometric assay (IRMA)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.19  Photometric assay

Photometric assay

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.21  Radioimmunoassay (RIA)

Radioimmunoassay (RIA)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.22  Radioimmunoassay (RIA): competitive method (CPBA)

Radioimmunoassay (RIA): competitive method (CPBA)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.07  Immuno assay systems
  • 03.02.07.23  Radioreceptor assay

Radioreceptor assay

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.09  Individual and specified hormones

Individual and specified hormones

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.09  Individual and specified hormones
  • 03.02.09.01  Diagnostic agents / kits for determination of growth hormones

Diagnostic agents / kits for determination of growth hormones

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.09  Individual and specified hormones
  • 03.02.09.02  Diagnostic agents / kits for determination of Leptin

Diagnostic agents / kits for determination of Leptin

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.12  Rheumatoid diseases

Rheumatoid diseases

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.12  Rheumatoid diseases
  • 03.02.12.01  Diagnostic agents / kits for diagnosis of rheumatism

Diagnostic agents / kits for diagnosis of rheumatism

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.12  Rheumatoid diseases
  • 03.02.12.04  Reagents for diagnosis of rheumatism

Reagents for diagnosis of rheumatism

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.14  Specific proteins

Specific proteins

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.14  Specific proteins
  • 03.02.14.01  C-reactive proteins (CRP)

C-reactive proteins (CRP)

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.15  Rapid tests - Immunochemistry

Rapid tests - Immunochemistry

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.15  Rapid tests - Immunochemistry
  • 03.02.15.01  Pregnancy tests

Pregnancy tests

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers

Tumor markers

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers
  • 03.02.17.01  Diagnostic agents / kits for tumour marker determination

Diagnostic agents / kits for tumour marker determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers
  • 03.02.17.03  Control material for tumour marker determination

Control material for tumour marker determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers
  • 03.02.17.04  Reagents for tumour marker determination

Reagents for tumour marker determination

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers
  • 03.02.17.05  Accessories for tumour marker determination

Accessories for tumour marker determination

  • 03  Diagnostics
  • 03.05  Infectious Immunology
  • 03.05.01  Bacteriology - Infectious immunology

Bacteriology - Infectious immunology

  • 03  Diagnostics
  • 03.05  Infectious Immunology
  • 03.05.06  Parasitology (Infectious immunology)

Parasitology (Infectious immunology)

Our products

Product category: Tumor markers

AFP ELISA

Alpha-fetoprotein (AFP) is a glycoprotein with a molecular weight of approximately 70 KD. AFP is normally produced during fetal and neonatal development by the liver, yolk sac, and in small concentrations by the gastrointestinal tract). After birth, serum AFP concentrations decrease rapidly, and by the second year of life and thereafter only trace amounts are normally detected in serum.
Elevation of serum AFP to abnormally high values occurs in several malignant diseases, most notably nonseminomatous testicular cancer and primary hepatocelluar carcinoma. In the case of nonseminomatous testicular cancer, a direct relationship has been observed between the incidence of elevated AFP levels and the stage of disease. Elevated AFP levels have also been observed in patients diagnosed with seminoma with nonseminomatous elements, but not in patients with pure seminoma.
In addition, elevated serum AFP concentrations have been measured in patients with other noncancerous diseases, including ataxia telangiectasia, hereditary tyrosinemia, neonatal hyperbilirubinemia, acute viral hepatitis, chronic active hepatitis and cirrhosis. Elevated serum AFP concentrations are also observed in pregnant women. Therefore, AFP measurements are not recommended for use as a screening procedure to detect the presence of cancer in the general population.

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Product category: Auto-immune diseases

ACPA (Anti-Citrullinated Protein Antibodies) ELISA

PRINCIPLE OF THE TEST

ACPA is bound to microwells. Antibodies against the coated antigen, if present in diluted patient sample, bind to the respective antigen. Washing of the microwells removes unbound unspecific serum and plasma components. Horseradish peroxidase (HRP) conjugated anti-human antibodies immunologically detect the bound patient antibodies forming a conjugate/antibody/antigen complex. Washing of the microwells removes unbound conjugate. An enzyme substrate in the presence of bound conjugate hydrolyzes to form a blue colour. The addition of an acid stops the reaction forming a yellow end-product. The intensity of this yellow colour is measured photometrically at 450 nm. The amount of colour is directly proportional to the concentration of antibodies present in the original sample.

SUMMARY AND EXPLANATION OF THE TEST

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. The main characteristic of RA is joint inflammation that results in joint damage and loss of function. An early diagnosis of RA and an immediate beginning of an appropriate treatment is important to prevent a complete joint damage. RA is diagnosed primarily on clinical manifestations and serological support has, up to now, been mainly restricted to the determination of autoantibodies against rheumatoid factor (RF). RF is a sensitive serological marker for RA with a moderate specificity of about 70%. In several studies it has been demonstrated that the determination of antibodies against citrullinated arginine residues in filament proteins occurs in RF negative patients. Citrullination is a peptidylarginine deiminase (PAD) catalyzed process in which the amino acid arginine (Arg) is modified to citrullin. During this conversion, the positively charged NH2-group is hydrolyzed to an oxygen group.

ACPA ELISA shows both a high specificity and a high sensitivity for auto-antibodies against mutated citrullinated vimentin. Vimentin is an omnipresent citrullinated protein which was observed in the rheumatoid synovial tissue of RA patients. There are recent findings of secernation and modification of vimentin by macrophages depending on pro-inflammatory signals. The titer of antibodies against vimentin in RA patients strongly correlates with the disease activity score (DAS).

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Product category: Biogene amines

3 CAT RIA

Intended use and principle of the test

Adrenaline (epinephrine), noradrenaline (norepinephrine) and dopamine are extracted by using a cis-diol- specific affinity gel, acylated and then converted enzymatically. The assay procedure follows the basic principle of radioimmunoassay, involving competition between a radioactive and a non-radioactive antigen for a fixed number of antibody binding sites. The amount of 125I-labelled antigen bound to the antibody is inversely proportional to the analyte concentration of the sample. When the system is in equilibrium, the antibody bound radioactivity is precipitated with a second antibody in the presence of polyethylene glycol. The precipitate is counted in a gamma counter. Quantification of unknown samples is achieved by comparing their activity with a reference curve prepared with known standards.

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Product category: Diagnostics / kits for the thyroid gland analyses (Auto-immune diseases)

Anti-R-TSH-Ab RIA

INTENDED USE

The TSH receptor autoantibody (TRAb) RIA kit is intended for use by professional persons only for the quantitative determination of thyrotropin receptor autoantibodies in human serum.  Hyperthyroidism in Graves’ disease is due to the presence of autoantibodies to the TSH receptor and measurement of these autoantibodies can be useful in disease diagnosis and management.

ASSAY PRINCIPLE

In this TRAb RIA kit TSH receptor autoantibodies in patient sera, calibrators and controls are allowed to interact with TSH receptor coated onto plastic tubes.  After a 2 hour incubation, the samples are discarded leaving TRAb bound to the immobilised TSH receptor.  Porcine TSH labelled with 125I is added in a 2nd incubation step, where it interacts with TSH receptors which have not been blocked by bound TRAb. Any unbound 125I TSH is then removed from the tubes by a wash step prior to counting on a gamma counter.  A lower level of radioactivity bound indicates the presence of TRAb in the test sample.

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Product category: Diagnostics / kits for the diabetes analyses

Anti-GAD ELISA

INTENDED USE 

The GAD 65  autoantibody (GADAb) ELISA kit is intended for use by professional persons only, for the quantitative determination of GAD autoantibodies in human serum. 
Autoantibodies to pancreatic beta cell antigens are important serological markers of type 1 diabetes mellitus (type 1 DM). The antigens recognised by these antibodies include insulin, glutamic acid decarboxylase (GAD 65  kDa isoform) and the islet cell antigen IA-2 or ICA-512. 


ASSAY PRINCIPLE
 

In DEMEDITEC’s GADAb  ELISA, GAD  autoantibodies in patients’ sera, calibrators and controls are allowed to interact with GAD 65  coated onto ELISA plate wells. After an 1 hour incubation, the samples are discarded leaving GAD autoantibodies bound to the immobilised GAD 65  on the plate. GAD 65 -Biotin is added in a 2 nd incubation step where, through the ability of GAD autoantibodies in the samples to act  divalently,  a  bridge  is  formed  between  GAD 65   immobilised  on  the  plate  and  GAD 65 -Biotin.  The amount of GAD 65 -Biotin bound is then determined in a 3 rd incubation step by addition of Streptavidin Peroxidase,  which  binds  specifically  to  Biotin.  Excess,  unbound  Streptavidin  Peroxidase  is  then washed away and addition of 3,3’,5,5’ – tetramethylbenzidine (TMB) results in formation of a blue colour. This reaction is stopped by addition of stop solution causing the well contents to turn yellow. The absorbance of the yellow reaction mixture at 450 nm and 405 nm is then read using an ELISA plate reader. A higher absorbance indicates the presence of GAD autoantibody in the test sample. Reading at  405  nm  allows quantitation  of  high  absorbances  (and  should  be  used  for  concentrations  of 200 U/mL or more). Low values (less than 10 U/mL) should be read off the 450 nm calibration curve. The measuring interval is 5 – 2000 U/mL.

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About us

Company details

Your expert for diagnostic laboratory products in routine and research

Demeditec Diagnostics GmbH is a privately owned company located in northern Germany. Since the foundation in 1987 Demeditec has rapidly grown to become a successful and reliable manufacturer and supplier of in-vitro diagnostic test kits. We are, therefore, proud to present an extensive product panel of non-radioactive (ELISA, PCR) and radioactive (RIA) test systems.

Our top-selling products are covering Human and Veterinary Diagnostics, Endocrinology - especially Salivary Diagnostics- , Infectious Diseases, Autoimmunity, Biogenic Amines and Tumor Markers.

Our customers are located worldwide and include private laboratories, hospitals, universities as well as other research institutions and pharmaceutical companies.

To ensure the quality of our products, services and support, Demeditec has been certified according to EN ISO 9001 and EN ISO 13485 since 2003 and according to the GMP standard since 2011. These certifications, along with qualified and creative personnel, enable the development of innovative test kits in our R&D department.

We welcome you to be a part of our network and hope to convince you of the quality of our products and support.

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