Service

Surfix BV

P.O. Box 286 , 6700 AG Wageningen
Dreijenplein 8 , 6703 HB Wageningen
Netherlands

Telephone +31 85 4881285
info@surfix.nl

This company is co-exhibitor of
IVAM Microtechnology Network

Trade fair hall

  • Hall 8a / G19
 Interactive Plan

Hall map

COMPAMED 2016 hall map (Hall 8a): stand G19

Fairground map

COMPAMED 2016 fairground map: Hall 8a

Our range of products

Product categories

  • 11  Manufacturing Services
  • 11.05  Coating

Coating

  • 11  Manufacturing Services
  • 11.16  Forming
  • 11.16.15  Surface treatment

Our products

Product category: Surface treatment

Nanowires

Nanowire based sensors have gained considerable interest as a general platform for ultrasensitive label-free electrical detection of biological and chemical species. These nanowire field effect transistor devices (NW-FETs) exhibit enhanced sensitivity compared to planar sensor platforms, due to the beneficial surface-to volume ratio of the nanowires, i.e. 1-D structure, which might enable single molecule detection.

In NW-FET devices the conductance through the nanowire is affected by the chemical environment, i.e. number of charged species, near the nanowire surface. Accordingly, modification of the nanowire with a molecular coating containing specific receptor-sites allows selective binding and consequent detection of chemical and biological species. In addition, by modifying individual nanowires in an array of nanowires with different receptors selective recognition of many different species in parallel can be accomplished, enabling high throughput screening for diagnostics and drug discovery.

Our surface modification technology has a number of benefits regarding the modification of NW-FET devices: 1) high reproducibility, 2) high chemical stability, 3) low number of interface traps at the organic-semiconductor interface, 4) selective modification of NWs, i.e. the surrounding surface is not modified.

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Product category: Surface treatment

Microfluidics

Microfluidics deals with minute volumes of fluid in a network of micrometer-scale channels and allows miniaturisation and integration of precious complex chemical, biological and physical processes. Due to the micro-scale dimensions and the resulting high surface-area-to-volume ratio microfluidic systems offer numerous advantages over conventional analytical and (bio)chemical methods, including faster reaction times, greatly enhanced analytical sensitivity, reduced sample and reagent consumption, excellent temperature control, easy automation and parallelisation, and portability. Furthermore, microfluidics offers the opportunity to integrate all benchtop laboratory routines from beginning to end in one device, also known as the “lab-on-a-chip” or “micro total analysis systems (µTAS)” concepts. As a result, literature contains thousands of reports describing almost innumerable biological, biochemical and chemical applications, making microfluidics one of the most promising and rapidly developing technologies of present time.

Due to the increased surface-area-to-volume ratio and the continuously increasing complexity of microfluidic systems control of the surface properties is essential, for instance to regulate the electro-osmotic flow (EOF) and to prevent biofouling. Via our proprietary surface modification technology the channel walls can locally be modified with our molecular nanocoating, even after bonding of the chip, i.e. inside the microchannels. Our nanocoatings possess a long-term chemical stability and allow implementation of a wide variety of terminal functional groups, like complex (bio)organic molecules such as antibodies, DNA, proteins, cells, catalytically and redox active moieties, and groups with biofouling properties.

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Product category: Surface treatment

Optofluidic Biosensors

Optofluidic sensor devices have emerged as a highly promising (bio)chemical and label-free sensing technology with potential application in fields like biomedical research, healthcare, pharmaceuticals, and water, food and environmental monitoring. As (bio)molecular binding events alter the refractive index contrast and thus the propagation of light through the optical sensing element, direct quantitative and kinetic information on the molecular interaction at the sensor surface can be obtained. As a consequence, optofluidic sensor devices have the perspective to become one of the most sensitive label-free (bio)sensing systems.

In order to fulfill all the above mentioned promises and expectations appropriate surface immobilization chemistry is of utmost importance. For instance, the current status in literature shows that the sensitivities are worse when performing measurements in more complex media, such as blood serum or tissue lysate, whereas many analytes of interest even require limits of detections in a range below what at present can be detected. In particular, non-specific binding of interfering (bio)molecules is a major issues and thus underlying surface chemistry that combines efficient analyte capturing with minimal non-specific binding remains an area of intensive research.

In addition, in most optofluidic sensing devices the actual sensing surface corresponds only to less than one percent of the total surface area of the chip, though commonly used surface modification approaches do not differentiate between the sensing surface and its surrounding surface area, i.e. all surface is coated with the same analyte capturing layer. It is obvious that, especially at low analyte concentrations, this is detrimental for sensitivity and reproducibility of the sensing event.

Via our proprietary surface modification technology, based on innovative nanocoatings, the surface properties of optical (bio)sensor devices can easily be controlled and tuned, enhancing for instance wettability and analyte capture efficiency and/or eliminating non-specific binding. Furthermore, it allows us to selectively modify the sensing surface of the chip with an analyte capturing layer and its surrounding surface with an antifouling layer, considerably affecting the sensing performance.

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About us

Company details

At Surfix, we believe that control of surface properties is essential for advanced micro- and nanotechnologies to be successful and revolutionize our world. Surfix develops and provides innovative custom-made nanocoatings for the micro- and nanotechnology market, based on chemical surface modification.With our proprietary surface modification technology even local and selective surface modification can be realized which enables the surface modification of complex geometries such as microfluidics, lab-on-a-chip and biosensors consisting of several materials.

We are a team of motivated people with extensive expertise in the field of organic, physical and biochemistry on surfaces, enabling us to span a ‘chemical bridge’ between biology and physics. As such Surfix has the ambition to operate as a market leader in advanced chemical surface modification and achieve the highest customer satisfaction. To this end we think along with our customers to provide custom-made solutions that facilitate our clients to achieve breakthrough innovations in their market.

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Company data

Sales volume

< 1 Mio US $

Export content

max. 50%

Number of employees

1-19

Foundation

2011