Immunoglobulin E (IgE) is a protein associated with allergic reactions; it is normally found in very small amounts in the blood. IgE is an antibody that functions as part of the body’s immune system, its defense against “intruders.” When someone with a predisposition to allergies is exposed to a potential allergen (such as food, grass, or animal dander) for the first time, they become sensitized. Their body perceives the potential allergen as a foreign substance and produces a specific IgE antibody that binds to mast cells (specialized cells in your tissues) and basophils (a type of white blood cell) in your blood stream. The mast cells are found in tissues throughout your body but are highest in concentration in your skin, respiratory system, and gastrointestinal tract. With the next exposure, these attached IgE antibodies recognize the allergen and cause the mast and basophil cells to release histamine and other chemicals, resulting in an allergic reaction that begins at the exposure site.
Experts in immunoassay development, Monobind has manufactured more than 200 million immunoassays since its inception in 1978 — ranking it as one of the largest in-vitro diagnostic producers. As an established industry player, the company provides ELISA and CLIA immunoassays, equipment and biological raw materials worldwide to market-leading distributors, laboratories, and manufacturers in the field of biotechnology.
Through its esteemed, internal R&D work and pioneering experience in reagent production, Monobind is able to deliver products that set a standard for high quality and affordable diagnostic healthcare.
Monobind is a 13485 & 9001 Certified Company, with CE Mark and US FDA Registration on its products. It is privately held corporation headquartered in Lake Forest, California