03.02.03.01 Diagnostics / kits for the diabetes analyses
Diagnostics / kits for the diabetes analyses
03.02 Immunochemistry (Immunology)
03.02.03 Auto-immune diseases
03.02.03.03 Diagnostics / kits for the thyroid gland analyses (Auto-immune diseases)
Diagnostics / kits for the thyroid gland analyses (Auto-immune diseases)
Product category: Auto-immune diseases
Indirect Immunofluorescence Assays
We provide a wide range of IFA products in detecting ANA, ANCA, AKA, dsDNA and Liver autoantibodies. IFA products contain high quality components and reagents that ensure excellent reproducibility and ease of use, and provide ideal morphology, discrete and clear results. Our cell culture and tissue section slides are available in both double and multiple substrates COMVI formats.
Both patient samples and control sera are added onto the slide. During incubation, the antibodies present in sera will specifically bind to target antigens. A secondary anti-human IgG antibody, conjugated with a fluorophore, recognizes and binds to the primary antibody. The attached fluorophore is then detected through fluorescent microscopy.
- Comprehensive menu (ANA/ANCA/dsDNA/LIVER/AKA) with flexible formats - Stable reagents with excellent compatibility - Superior sensitivity with idea morphology for easy result interpretation - Automation available
Line Immuno Assays (LIA) for the Detection of Auto- antibodies
Comprehensive panels for the detection of IgG autoantibodies against cell nucleus, vasculitis and Liver antigens. The assays are intended for in vitro diagnostic use only as an aid in the diagnosis of autoimmune diseases such as Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD), vasculitis, Primary Biliary Cirrhosis (PBC) and so forth.
Test Principle Nuclear and associated cytosolic antigens are applied as lines on nitrocellulose membrane strips. The strip is first blocked to prevent nonspecific bindings. During incubation, autoantibodies present in the patient sample bind to the antigens on the strip. An alkaline phosphatase labeled anti-human IgG antibody is used to detect the bound auto-antibodies. After addition of the substrate solution, the appearance of purple blue lines indicates the existence of auto-antibodies against the corresponding antigens.
Features and Benefits
- Built-in Control line and Cut-off line in each strip for intuitive reagent quality validation and easy result interpretation - Stable reagents with excellent compatibility - High signal to noise ratio due to minimized background - High strip-to-strip and reagent lot-to-lot reproducibility - Accurate and objective result interpretation through Software - Automation available
Enzyme linked immunosorbent assay (ELISA) has the following advantages compared to LIA and other immunoblotting methods:
- Classic and standard test method, simple and fast procedure; - Quantitative detection achievable through standard curve; - Detachable MPP, reagent cost saving; - Objective result interpretation; - Full automation.
HOB Biotech Group (HOB) is one of China’s best IVD companies, with the focus on immunodiagnostic products. Especially for allergy & autoimmune disease diagnostics, HOB is the market leader in China. With our strong R&D capability and high quality manufacturing operation, HOB provides high quality products at very competitive prices to customers worldwide and keeps the market leader position in China.
HOB R&D team is composed of more than 30 researchers & scientists, led by world-class scientists& management team coming back from USA. Our ISO13485 certified 4000 square meters manufacturing plant is among the best of the industry in China. The company was first founded in 1996 as a distributor for USA/Europe imported products. It then transformed into a manufacturing plant with R&D capability, making products at the same high quality standards as USA/Europe made products, but much lower costs. HOB has achieved fast growth with its national sales coverage in the emerging Chinese market. Now we are expanding our growing business internationally, utilizing our high-quality low-cost manufacturing and strong R&D capabilities. We welcome distributors, OEM partners and other joint development opportunities worldwide.
HOB’s vision is to become a world class IVD company while keeping its China leading position in the markets it competes.
We sincerely hope to establish a long-term distribution partnership with you. We are committed to providing high quality products, service & supportat competitive prices.
HOB’s founders and key management team members have worked in the USA for multi-national corporations for many years. This has made HOB an internationally oriented company ever since its establishment. We follow the international rules and practices, while keeping our Chinese cultural in heritage. HOB’s business philosophy is mutual trust and benefits.
HOB is always looking for new distributors for our diagnostic reagents to expand our global distribution network.If you are a professional distributor, specialized in medical, or better, diagnostic products, and if you are interested in becoming a member of the HOB family, please contact us.
HOB is capable of manufacturing a very wide range of diagnostic products in our state-of-the-art facility. We are interested in forming a partnership with our OEM partners and willing to make custom-modifications of our products for you.
We can supply our products on OEM conditions, tailor-made to fit your unique market needs. We can manufacture for you bulk products or ready-for-use kits in the design of our OEM partner, or any other format. If you are interested, please contact us.
Manufacturing & Quality
Quality assurance is the corner stone of our success. Our manufacturing site in Suzhou city is registered to ISO 13485 and complies with the requirement of SFDA for the in vitro diagnostics.
HOB manufactures diagnostic products of highest quality in full compliance with quality system standards (ISO 13485:2009). The most modern equipment operated by well-trained personnel guarantees the greatest reliability and lot-to-lot consistency.
At all times compliance with relevant statutory, regulatory and legal requirements is ensured.One of the keys to our success is the continuous optimization of our comprehensive Quality Management System.