Semiotik, LLC

Miklukho-Maklaya Str., Bld. 15, 16/10, 117437 Moscow
Russian Federation

Telephone +7 903 5377531

This company is co-exhibitor of

Trade fair hall

  • Hall 17 / B04
 Interactive hall map

Hall map

MEDICA 2016 hall map (Hall 17): stand B04

Fairground map

MEDICA 2016 fairground map: Hall 17

Our range of products

Product categories

  • 03  Diagnostics
  • 03.02  Immunochemistry (Immunology)
  • 03.02.17  Tumor markers

Our products

Product category: Tumor markers

Microchip for diagnostics

Release of microchips for diagnostics - 2016.

Diagnostics of:

 • breast cancer
 • lung cancers
 • ovarian cancer
 • colorectal cancer
 • autoimmune syndromes
 • TORCH and other infections
 • …

Number of other antibodies are revealed, including:

 • Blood group antibodies against АВН, Lewis, FS, RhD antigens
 • xeno-antibodies aGal (Galili) and HD (Hanganutsu-Diecher)
 • PEG and hyaluronate
 • …

The microchip parameters

 • 25 х 75 mm size.
 • time needed for typical analysis is ~3 hr.
 • About 400 glycans, 200 bacterial polysaccharides, peptides, proteins are immobilized, all in 6 replicates.
 • specific IgG and IgM are measured separately.
 • Storage time - 1 year at +4oC
 • Mathematical algorithm used for search of diagnostic signatures is presented

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Product category: Tumor markers

Ligands on a microchip

Glycans and polysaccharides are the microchip ligands for the diagnostics of oncological, autoimmune and infectious diseases because:
 • Carbohydrate antigens in cells are most plastic towards pathological changes
 • A considerable part of antibodies in human blood is directed to carbohydrates
 • Carbohydrate antigens are chemically stable; their conformation does not become changed after chemical immobilization
 • Principal antigens of bacteria are polysaccharides; they are species specific features  
 • Core structures of O-chains and N-chains of glycoproteines;
 • Oligosaccharides from lipids;
 • Antigens of blood groups АВ0, Ii, P;
 • Antigens of blood group Lewis, and their sulfated and sialylated analogs;
 • Synthetic carbohydrates: unnatural and those not common for mammals.

Information on a part of glycans presented on glycochip is open for users. It includes antigens of blood group systems ABH, Lewis, FS, Ii. This information may be useful during transfusions and transplantations, assay of mother/fetus incompatibility, etc.

Information about some glycans in composition of diagnostic signatures of the microchip is confidential for researchers and can be provided after the contact with Semiotik.

Bacterial polysaccharides
 • Polysaccharides of pathogenic bacteria
 • Polysaccharides of opportunistic pathogenic bacteria

These microorganisms include:
Shigella flexneri, Shigella dysenteriae, Shigella boydii, Salmonella enterica, Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Proteus vulgaris, Proteus pinneri, Cronobacter sacazaki, etc.

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About us

Company details

Semiotik LLC was established in October 2013 for development and production of diagnostic test-system (micpochip) intended for concurrent diagnostics of oncologic, infectious and autoimmune diseases.

Microchip allows analyzing samples of blood or plasma for several hundred specific immunoglobulins.

Microchip gives possibility of detecting about 100 pathologies at the same time. This can considerably simplify and decrease the costs of procedure of blood/plasma analysis. At present the potential of diagnostic based on determination of blood antibodies is undervalued; development of multi-antigen chip will lead to a breakthrough.

Due to the presence of tumor-specific glycans the developed microchip will provide a possibility of performing diagnostics, prognostics, monitoring and theranostics of oncology diseases at new level.

Format of analysis and technology of production allows increasing the number of antigens of a chip extending the range of its applications. Low prime cost makes possible the formation of new niches for wide use of this product.

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Company data

Sales volume

< 1 Mio US $

Export content

> 75%

Number of employees




Area of business