Animal Producer at COMPAMED -- COMPAMED Trade Fair
Photo: Spider
Spider silk is very steaddy and
elastic; © Messe Duesseldorf

The animals and their use are presented by the Department of Plastic, Hand and Reconstructive Surgery of the Hannover Medical School. Sarah Strauß protects the animals carefully which are postbred in "Spidersilk Laboratory" – to the protection of endangered species for the sake of. „The spider oaths is many-sided applicable – for example, as a seam material, to the nervous regeneration and treatment of wounds, because they is extremely stretchy and tear-proof“, explains the biologist.

In the majority bull model could be already proved that the spider oaths well as a matrix for the Tissue engineering is suited. Skin as well as cartilage can be bred on this material.

Photo: Hands with spider silk on a reel
200 to 500 metres of silk thread can produce the females who live in the college in 30 to 40 square metre rooms; © Messe Duesseldorf

To repair again destroyed nervous connections, nerves had to be taken up to now by other body places. The spider oaths takes this step superfluously, because she can substitute for the missing place of the connection. Besides, she serves, so to speak, as a guide bar. The advantage: The nerve grows to it again and the cells of the silk break up after a time by itself. „Repulsions and allergies could not be observed up to now“, stresses the biologist.

In the lab the kinds which are investigated are also postbred to receive them. „Our draught is unique“, knows Strauss. „In most other institutes is either done research or is bred.“ The forefathers of both spider ladies who belong to the type Nephila edulis come from Australia and have given birth on the way to the COMPAMED unexpectedly boy which they have wrapped as a precaution in cocoons. 200 to 500 metres of silk thread can produce the females who live in the college in 30 to 40 square metre rooms.

Photo: Axolotl soft toy 
Animal role models for
regenerative medicine;
© Messe Duesseldorf

Axolotl: An axolotl donates an enzyme

For the reason of animal protection the Axolotl which are amphibians are not present at the booth; they are only to be seen as soft toys. Nevertheless, their unique characteristics are presented. „The amphibians sometimes bite off each other’s limbs. However, this is no drama for the animals, because these limbs grow again,“ according to Sarah Strauß. The enzyme responsible for it is called "AmbLOXe" and is also investigated for the application in regenerative medicine.

Because the clinic is specified, among the rest, on combustion victim, one sees big potential there: „If combustion on the skin was treated by mice with the enzyme AmbLOXe, the sore surface was substantially smaller after one week than without protein“, describes Strauss and complements: „We could recognise a positive scarring – what could be especially valuable in future just for patients with extreme combustion.“

In the state of the college, enthusiasts can get an insight as the "products" of the animals can be processed in the medicine.

Natascha Mörs