Worldwide, the examination data of 175 ventilator patients have been recorded and evaluated in the RESCUE-3 study so far, 35 of them from Greifswald. Greifswald University Medical Center is thus the leading study center worldwide for the new procedure.
"We have been able to gain extensive experience with electrostimulation of the diaphragm at Unimedicine," emphasized Prof. Dr. Ralf Ewert, head of the Pneumology, Infectious Diseases and Weaning Center at Greifswald University Medical Center. "As a result of the corona pandemic, we have many more men and women who require intensive care and are temporarily dependent on artificial ventilation. In the overall spectrum of efforts to wean patients off long-term ventilation, this method is increasingly taking a firm place. From the perspective of our treatment team, the results to date are promising. It is also very gratifying that the system has been fundamentally refined and made more practical within a short period of time."
Flaccid diaphragm reactivates Diaphragmatic dysfunction is commonly observed when weaning from invasive mechanical ventilation. Ventilators use positive pressure to force air into the lungs so that the main breathing muscle, the diaphragm, is not stressed. Especially with prolonged ventilation, the diaphragm, a plate of muscles and tendons between the chest and abdomen, loses strength and functionality. There is a risk of a so-called ventilation-induced diaphragmatic dysfunction. This is where the procedure from Canada comes in, which has been undergoing intensive testing worldwide for two years. The diaphragm and the phrenic nerves are stimulated via a catheter to restore diaphragm strength and enable natural, independent breathing.
Meanwhile, the entire mobile console with the control unit has been optimized, significantly shortening the preparation for therapy. There is now an almost automated process in the treatment with electrostimulation. The catheter can be placed by means of a connected ECG, which can be used during catheter insertion or immediately thereafter.. Whereas previously the catheter could "only" stimulate the diaphragm, it is now also suitable for infusing drugs and fluids in intensive care patients. The technically modified electrodes on the catheter provide a better coupling to the phrenic nerves. The AeroPace neurostimulation console sends a signal to the electrodes on the AeroPace catheter to stimulate the phrenic nerve. Like a personal trainer, the exercise intensity can be adjusted to provide repetitive exercises for the diaphragm muscle, depending on the individual's situation.
"We will certainly continue to bring this method to bear outside of the ongoing clinical trial, as we are convinced of its effectiveness. In our experience, electrostimulation of the diaphragm is a useful addition to the extensive efforts to wean patients off long-term ventilation," the pulmonologist said. "The goal is to significantly reduce artificial ventilation time."
COMPAMED-tradefair.com; Source: Universitätsmedizin Greifswald
