New advances: graphene-based sensor for medical diagnostics

Graphene is an exceptionally sensitive material, making it a promising candidate for the development of highly effective biosensors. A graphene-based biosensor could detect the tiniest changes in electrical properties when molecules interact with the graphene surface. However, a major challenge has been the necessary functionalization of graphene. In order to detect specific biomarkers in blood or saliva samples, the sensor needs a functionalized surface to which specific molecules can bind. 

Prof. Andrey Turchanin from the University of Jena, explains: "If graphene is functionalised directly, its electronic structure changes unfavourably." This change interferes with the parameters critical to the high sensitivity of the biosensor, making practical application difficult. 

According to the researchers, this breakthrough could have significant implications for the future of diagnostics. "It is much more sensitive, significantly faster - the results are available in around five minutes - and cost-effective if it is produced in large quantities.", says Kaiser. The sensor operates purely on electrical principles - changes in electrical current indicate the presence of the targeted biomarkers. This makes it possible to integrate such a biosensor into everyday clinical practice, potentially even using mobile devices.  

MEDICA-tradefair.com; Source: Friedrich-Schiller-Universität Jena