The flagship project B1 develops imaging systems for highly scattering media such as biological tissue. In such environments, scattering, absorption, and reflection caused by molecules, pigments, or cells lead to wavefront distortions. These effects significantly limit imaging depth and image quality in conventional optical systems.
To address this, Fraunhofer IPMS has developed specialized spatial light modulators. These devices consist of thousands to millions of individually controllable micro-mirrors that can be actuated at high speeds in the kilohertz range. By adapting the light wavefront in real time, optical distortions can be corrected in a targeted manner.
This enables high-resolution imaging even in deep and strongly scattering tissue layers. Potential applications include microscopy and endoscopy for deep tissue imaging. The aim is to support non-invasive diagnostics, for example in cancer detection, improve treatment monitoring, and advance biomedical research for physicians and researchers.
“The challenges in optical imaging are diverse and complex. With this project, our goal is to develop technical solutions and explore the boundaries of what is possible,” explains Prof. Harald Schenk, Managing Director of Fraunhofer IPMS and Professor of Micro- and Nanosystems at BTU Cottbus. “Only the high speed and precision of the microscopic, movable micro-mirrors enable decisive image corrections and increased resolution, expanding diagnostic possibilities in medicine. This makes it possible to examine deep tissue layers for changes that were previously inaccessible to optical methods.”
COMPAMED-tradefair.com; Source: Fraunhofer Institute for Photonic Microsystems
