03.02.17.04 Reagents for tumour marker determination
Reagents for tumour marker determination
Product category: Fertility / Pregnancy hormones / Proteins, Units and systems for hormone determination, Reagents for hormone determination
Acites (In-Vivo) Production
Ascites production of monoconal antibody is produced in vivo in ascites fluid. Production in ascites fluid is nearly always the most economical method of monoclonal antibody production; your cost per milligram of monoclonal antibody is the lowest. For monoclonal antibodies produced repeatedly in large quantities, SDIX offers an ascites optimization process to maximize production efficiency and minimize animal use. Please inquire.
All incoming cell lines require pre-production verification.
Viability check of cell line
Strains: Balb/c, ICR SCID, CAF1 are available, please contact us for additional strains
Lot Size 50 -2000 mice per lot (> 500 mice needed, please call for availability)
Ascites fluid is harvested over multiple taps
At completion all taps are pulled and centrifuged
Final IgG concentration is determined
Final product stored at -20oC
Average ascites volume per mouse is 3-5mls/mouse and average antibody concentration is 3-5mg/mL.
Timing 2-3 months
Monoclonal Cell Line Optimization for Antibody Production
Large Scale (mgs to kgs) Monoclonal Antibody Production (In Vivo and In Vitro)
Cell Storage and Banking
Bioprocessing - Monoclonal
Large Scale cGMP Production of Polyclonal Antibodies
SDIX is a wholly owned subsidiary of OriGene Technologies, specializing in high quality, large-scale GMP antibody production in the U.S.; Delaware and Maine.
For over 25 years, SDIX has been a leading immuno-solutions company, developing results-oriented and innovative antibody-based solutions that enable customers, world-wide, to meet high performance diagnostic and commercialization objectives. All sites are ISO 13485:2003 certified and the manufacturing site in Delaware is FDA and MHRA registered for the manufacture and export of class I IHC reagents and kits.
For IHC applications, over 40 CE-marked IVD reagents are manufactured and sold in the EU and US. Other products include critical reagents such as antibodies to Troponin I, Strep A, CRP, Apo A1, ApoB, Micro-albumin and Calibrators. SDIX also provides both polyclonal and monoclonal antibody development and production services, including long term supply of monoclonal antibodies for IVD and drug development applications as well as polyclonal antibody production in goat, rabbit and other species.
In the life science market, SDIXs technology and capabilities are being used to help discover disease mechanisms, facilitate development of new drugs, and provide antibodies and assays utilized in the diagnosis of disease.