ZytoVision GmbH of Bremerhaven at MEDICA 2017 in Düsseldorf -- COMPAMED Trade Fair
Manufacturers

ZytoVision GmbH

Fischkai 1, 27572 Bremerhaven
Germany

Telephone +49 471 4832-300
Fax +49 471 4832-509
info@zytovision.com

This company is co-exhibitor of
DiagnostikNet-BB Netzwerk Diagnostik Berlin-Brandenburg e.V.

Hall map

MEDICA 2017 hall map (Hall 3): stand G60

Fairground map

MEDICA 2017 fairground map: Hall 3

Our range of products

Product categories

  • 03  Diagnostics
  • 03.01  Clinical chemistry
  • 03.01.07  Gene tests / molecular biological diagnostic

Our products

Product category: Gene tests / molecular biological diagnostic

ZytoDot 2C

Introduction
ZytoDot® and ZytoDot® 2CTM products are designed for the detection of aneuploidies, gene amplifications or gene deletions and translocations by Chromogenic in situ Hybridization (CISH) in formalin-fixed, paraffin-embedded tissue sections, cell samples, blood or bone marrow smears, and metaphase chromosome spreads. The advantages of CISH are:

  • Simultaneous observation of tissue morphology and CISH signals
  • Quick and easy interpretation of results comparable to IHC
  • Storage of slides at room temperature - CISH signals are permanent
  • No costly fluorescence microscope needed

Method Description - ZytoDot®
Single Color CISH for the Detection of Genomic Alterations
The ZytoDot® system uses Digoxigenin-labeled probes which are detected using a Mouse-anti-Digoxigenin antibody. This antibody is detected by a polymerized HRP-Goat-anti-Mouse antibody. The enzymatic reaction of DAB leads to the formation of strong permanent brown signals that can be visualized by light microscopy using a 40x objective.
 
Method Description - ZytoDot® 2CTM
2-Color CISH for the Detection of Genomic Alterations

The ZytoDot® 2CTM system uses DIG- and DNP-labeled probe cocktails targeting different genomic sections which are detected using a Mouse-anti-DIG/Rabbit-anti-DNP cocktail. These antibodies are detected by a unique cocktail of polymerized HRP-Goat-anti-Mouse/AP-Goat-anti-Rabbit antibodies. The enzymatic reaction of AP-Red and HRP-Green leads to the formation of strong permanent red respectively green signals that can be visualized by light microscopy.

 
ZytoDot® Kits and ZytoDot® 2CTM Kits – Convenient Solutions
  • All single color ZytoDot® CISH probes can be combined with the ZytoDot CISH Implementation Kit (C-3018-10/-40)
  • All dual color  ZytoDot® 2CTM CISH probes can be combined with the ZytoDot 2C CISH Implementation Kit (C-3044-10/-40)

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Product category: Gene tests / molecular biological diagnostic

VisionArray

VisionArray ® HPV Chip – Fast and Reliable Genotyping
The human papillomavirus (HPV) has been conclusively identified as the major risk factor for cervical cancer. It is the third most common cancer in women worldwide, with an estimated number of 530,000 new cases and 280,000 deaths each year. Over the last years the relevance of HPV in the history of oropharyngeal cancers has become more and more important which is indicated by a dramatically risen number of cancers of the oral cavity and pharynx linked to HPV. Currently more than 150 HPV types are well characterized which are classified as high-risk and low-risk types depending on the risk of progression from mild dysplasia to cancer.

VisionArray ® HPV Chips
VisionArray ® HPV Chip 1.0 - Detection of 41 HPV Types

The VisionArray HPV Chip 1.0 is intended to be used with the VisionArray Analysis Package for the qualitative detection and genotyping of PCR amplificates of 12 high-risk, 12 probably high risk, and 17 low-risk Human Papilloma Virus (HPV) genotypes that have been produced with the help of the VisionArray HPV Primer Kit and the VisionArray Detection Kit.

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Product category: Gene tests / molecular biological diagnostic

ZytoFast PLUS

Introduction
The ZytoFast® products are designed for outstandingly fast detection and discrimination of human pathogen viruses, e.g. HPV, EBV, CMV, and the determination of lymphocyte clonality by detecting Ig-κ and Ig-λ light chain RNA by Chromogenic in situ Hybridization (CISH) in formalin-fixed, paraffin-embedded tissue sections and cell samples. The signal intensity of ZytoFast® probes is increased even more when using the  ZytoFast® PLUS Implementation Kits.

Method Description - ZytoFast®
The ZytoFast® system uses oligonucleotide probes tagged with Biotin which are detected using enzyme-conjugated streptavidin targeting the tag. The enzymatic reaction of chromogenic substrates, e.g. BCIP/NBT or AEC, leads to the formation of strong color precipitates that can be visualized by light microscopy.

Method Description - ZytoFast® PLUS
The ZytoFast® PLUS system uses Digoxigenin-labeled probes which are detected using primary antibodies. These antibodies are detected by polymerized enzyme-conjugated secondary antibodies. The enzymatic reaction of chromogenic substrates, e.g. NBT/BCIP, AEC or DAB, leads to the formation of strong color precipitates that can be visualized by light microscopy.

ZytoFast® - Flexibility that meets your needs 
  • All Biotin-labeled probes can be combined with a ZytoFast® CISH Implementation Kit
  • All Digoxigenin-labeled probes can be combined with any of the ZytoFast® PLUS CISH Implementation Kits

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Product category: Gene tests / molecular biological diagnostic

VisionArray ® DNA Extraction, PCR, and Detection

VisionArray ® FFPE DNA Extraction Kit

The VisionArray FFPE DNA Extraction Kit is designed to be used for the isolation of genomic DNA from formalin-fixed, paraffin-embeded (FFPE) specimens. The professional use of this purification system optimized for FFPE samples results in highly purified nucleic acid samples. The purified DNA can be used directly for PCR with the VisionArray HPV Primer Kit, the VisionArray PreCise Taq DNA Polymerase, and the VisionArray Uracil-DNA (UDG) Glycosylase.

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Product category: Gene tests / molecular biological diagnostic

VisionArray ® Detection Kit

The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray Primer Kit, the VisionArray PreCise Taq DNA Polymerase, the VisionArray Uracil-DNA (UDG) Glycosylase, and the corresponding VisionArray DNA Chip. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArrayChips.

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About us

Company details

Our Vision – Molecular Diagnostics Simplified
It all started with a vision: to develop and produce innovative in vitro diagnostic products, primarily for tumour diagnosis, based on the technique of in situ hybridization. That vision has since become reality, with the result that the name »ZytoVision« is identified the world over with technological and cost leadership in this field.

Our company – a privately managed enterprise based in Bremerhaven, Germany – has been operating successfully in the international market for more than 10 years and is widely regarded as a pioneer in high-quality diagnostic devices. More than 50 employees are working continuously to develop, improve, produce and package our products. And we are steadfast in our goal of ensuring that our product portfolio is always complete and up-to-date in our core areas of solid and haematological tumour diagnostics. Our more than 250 CE-certified IVDs (in vitro diagnostic devices) are already being used in more than 60 countries around the world.

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