Metisafe Concept Modular Cleanroom
Metisafes Unique Approach to Building Modular Cleanrooms
Adaptation of Metisafes instrument manufacturing line into cleanrooms have been achieved by keeping the following criteria:
Applying box-in-box design, which is independent of the facility building
Using low noise high-efficiency particulate air (HEPA) fan units instead of only HEPA filters
Integrating optimal airflow patterns of safety cabinets or laminar airflow (LAF) units
Designing negative plenum wall panels and ceiling
Using precise machined full steel structure
Integrating total automation control
With this concept, Metisafe has taken LAF cabinets as the base for its several pre-engineered positive pressured cleanroom models.
Validation guaranteed application-specific models have been operating since 2006 in cell culture labs and non-hazardous sterile compounding units, to name but a few.
Building material
Ex-factory standardized negative pressured biosafety models have been transformed from biological safety cabinets (BSC). Tuberculosis labs, virology labs, hazardous drug compounding, BSL-2 and BSL-3 facilities have been running without reconstruction needs of units.
Usage of the sheet steel material in cleanroom components makes it possible to build stronger free-standing structure and leak-proof panel connections. Manufacturing of mono-block and corner radiused wall panels are the other advantages of steel material.
Negative plenum technology
Metisafe uses negative plenum technology in all of its designs as default. Pre-engineered recirculation ducts and leak-proof ceilings provide increased particle sweeping efficiency and energy saving.
Particle leakage from surroundings through increased pressured ducts of the building is also prevented by using this method. Achievement of more homogenous temperature distribution by the help of negative plenum increases airflow pattern safety and personnel conformity while operations are in progress inside.
In general, traditional cleanrooms are designed as building dependent and construction based. The Metisafe cleanroom concept, however, is designed as an individual operating instrument.
By using standard equipment and dimensions, Metisafe is having the advantage of sustainable comfort and performance developments in its designs such as more energy-saving methodologies, active noise control applications and automated decontamination.
User-friendly
On the user side, having an instrument concept cleanroom has much more advantages than traditional designs. These benefits include:
Design & manufacturing phase:
More than 100 models for selection suitable to any empty space
Cleanroom performance validated more than 30 models without the need for new design qualification
Minimal installation requirement: Only the power source, chilled water supply and air ducts
Installation and set-up phase:
Fast assembly at the site. In general, days to a couple of weeks depending size of the model
Clean and easy assembly and installation at the site without disturbing the other rooms
Easy commissioning and acceptance because of manufacturing with predefined criteria like a standard instrument
Operation:
Proven increased cleanroom life without loss of operational performance
More accurate measuring & warning system for improper operation
Demounting and reassembling availability by keeping its specifications
Years of cleanroom performance test success without any reconstruction
Maintenance:
Defined breakdown rates based on more than ten years of field data
Optimized cleanroom performance with much lower energy use
Incompatible low maintenance cost
Decreased yearly validation costs
Performance and maintenance data of sites in operation for more than 10 years prove that the total investment and operation cost are much lower than conventional cleanroom constructions.
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