RheoMeditech Inc.

RheoSCAN
DIABETIC COMPLICATION SCREENING ASSAY in LESS THAN A MINUTE
•Diabetic Nephropathy
•Diabetic Retinopathy
•Metabolic syndrome



[ Innovative Technology for Hemorheology ]

RheoSCAN-AnD300 can measure comprehensive rheological properties of blood within a short time (< 2 min). Now, RBC deformability, aggregation and aggregating force can be easily measured with a leading-edge microfluidic technology.



• Deformability : EI@3Pa, EImax, t1/2
• Aggregation : AI, M, ESR, t1/2
• Aggregating force : critical shear stress (CSS)
• Due to the quick and easy operation, RheoSCAN can be used at research laboratories and clinical environments.


RBC Deformability
- Sample volume :5㎕
- Testing Time : 30 s
- Microfluidic
- Laser Diffraction

RBC Aggregation
- Sample volume : 8㎕
- Testing time : 120 s
- Microfluidic Stirring
- Light Transmission

Critical Shear Stress
- Sample volume : 500㎕ (=0.5mL)
- Testing Time : 30 s
- Microfluidic shearing
- Light Backscattering



[ RheoSCAN Features ]

EARLY DETECTION
- RheoScan system shows significantly high correlation with DKD, DR, and MetS through CSS

FAST
Rapid test: the test takes less than a minute (30~60, 120 seconds)

SIMPLE AND EASY
- One step of pipetting
- Disposable microchip
- Automated operation

TARGETED
- Diabetes Mellitus
- Diabetic Complications
- Diabetic Retinopathy (eye)
- Diabetic Nephropathy (kidney)
- Metabolic Syndrome
- Anyone who want's to check their health status


Visit our website for more information
www.rheoscacn.com
www.any-sis.com/rheoscan

Anysis System is a platelet function testing system that measures bleeding risk managing assessments, and anti-platelet therapy response assessments for inherited, acquired, or drug-induced platelet dysfunction. Through in-vivo vascular mimicking microfluidics, the system measures a realistic primary hemostasis associated with platelet function.

▶ Test Types 
•  Anti-platelet Therapy Response Assessment
   Anysis-Aspirin
   Anysis-P2Y12 
•  Bleed Risk Screening
   Anysis-C/ADP
   Anysis-C/Epinephrine

Test Time: less than 5 minutes
The device includes two kit insertions which makes it possible to run two tests at a time.
Requiring blood sample: 200uL (sodium citrated)

▶ Key Features
1) Fully Automated System : With a single pipetting, the whole test is automatically operated
2) Bubble-free Test : Air bubbles in blood sample are naturally excluded in the test
3) Hematocrits-independent : Hematocrit variations do not affect the measurement of Anysis
4) Operator-independent Results : Measurements are not affected by operator's skillfulness
5) Stenosed Thrombosis Model : Flow through microbeads mimics stenosed vascular thrombosis
6) Platelet-adhesion Characteristic : Adhesion characteristic is fully emphasized in microscale pores


Upstream activation, which frequently occurs in pathological vascular environments, can be mimicked by adopting a shear-generating stirrer in a sample chamber.
After activation, the blood flows through a microfluidic tube including a flow-closure section consisted of ECM-coated microbeads. Typical ECMs are collagen and fibrinogen.
Downstream Adhesion of activated platelets occurs, followed by aggregation of platelets.
As the adhesion and aggregation of platelets continues, the flow paths through packed microbeads are gradually blocked and the blood flow eventually stops.
Measurement of how far the blood has migrated is the index for assessing the platelet function. The longer the distance migrated, the stronger the dysfunction of the platelets.

RheoESR
Erythrocyte Sedimentation Rate

ESR in 20 SECONDS BY RED CELL AGGREGATION
Body inflammation /Immune response system
Chronic disease, an immune disorder, or other medical condition