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PANAGENE Inc.
54, Techno 10-Ro, Yuseong-gu,
34027
Daejeon
Korea, Republic
Korea, Republic
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Our range of products
Product categories
- 03 Diagnostic tests
- 03.06 Genetic testing, molecular diagnostics
- 03.06.01 DNA testing
DNA testing
- 03 Diagnostic tests
- 03.06 Genetic testing, molecular diagnostics
- 03.06.03 Polymerase chain reaction (PCR)
Polymerase chain reaction (PCR)
- 03 Diagnostic tests
- 03.06 Genetic testing, molecular diagnostics
- 03.06.04 Other molecular diagnostics testing
Other molecular diagnostics testing
Our products
Product category: Polymerase chain reaction (PCR), Other molecular diagnostics testing, DNA testing
PANAMutyper™
PANAMutyper™ is a novel technology that integrates PNAClamp™ and PANA RealTyper™.
PNAClamp™ is a PCR technology and uses PNA (Peptide Nucleic Acid) probes which bind to the wild-type DNA complementarily. These PNA probes restrain the amplification of wild-type DNA so small amount of mutant-type DNA is selectively amplified which makes possible to detect somatic mutation only. PANA RealTyper ™ is Multiplex Melting Curve Analysis using fluorescence labeled PNA probe. PANAMutyper™ takes advantages from both technologies.
It is not only able to detect small amount of mutation with high sensitivity, but also able to genotype multiple mutations simultaneously using the phenomena that has their own melting temperature(Tm) value for the sequence changes of the target gene.
The available products are EGFR, EGFR v2 (C767S included), KRAS, NRAS, BRAF, EML4-ALK, ROS1.
PNAClamp™ is a PCR technology and uses PNA (Peptide Nucleic Acid) probes which bind to the wild-type DNA complementarily. These PNA probes restrain the amplification of wild-type DNA so small amount of mutant-type DNA is selectively amplified which makes possible to detect somatic mutation only. PANA RealTyper ™ is Multiplex Melting Curve Analysis using fluorescence labeled PNA probe. PANAMutyper™ takes advantages from both technologies.
It is not only able to detect small amount of mutation with high sensitivity, but also able to genotype multiple mutations simultaneously using the phenomena that has their own melting temperature(Tm) value for the sequence changes of the target gene.
The available products are EGFR, EGFR v2 (C767S included), KRAS, NRAS, BRAF, EML4-ALK, ROS1.
Product category: DNA testing, Polymerase chain reaction (PCR), Other molecular diagnostics testing
PANA RealTyper™
PANA RealTyper™ (PNA probe-based fluorescence melting curve analysis) is based on the change in fluorescent signal as a sample thermally denatured (melting temperature shift).
PANA RealTyper™ is a powerful tool for mutation detection (screening and genotyping) by a single probe.
PANA RealTyper™ can distinguish multiple SNPs adjacent to each other on a short target region.
This method offers easy and simple data analysis without using analyzing software because of its clarity of melting peak.
PANA RealTyper™ can be applied in the field of personalized medicine, origin discrimination and detection of multidrug-resistant microorganisms.
The available products are HPV Genotyping (40 Subtypes), STD (13 Pathogens), HPV Screening (16 Subtypes), and CRE (6 CRE Types).
PANA RealTyper™ is a powerful tool for mutation detection (screening and genotyping) by a single probe.
PANA RealTyper™ can distinguish multiple SNPs adjacent to each other on a short target region.
This method offers easy and simple data analysis without using analyzing software because of its clarity of melting peak.
PANA RealTyper™ can be applied in the field of personalized medicine, origin discrimination and detection of multidrug-resistant microorganisms.
The available products are HPV Genotyping (40 Subtypes), STD (13 Pathogens), HPV Screening (16 Subtypes), and CRE (6 CRE Types).
Product category: DNA testing, Polymerase chain reaction (PCR), Other molecular diagnostics testing
PNAClamp™
PNAClamp™ technology is the PNA-based PCR clamping that selectively amplifies only the mutated target DNA sequence as a minor portion in the mixture with the major wild type DNA sequences. PNAClamp™ technology takes full advantages of PNA probes that have strong binding affinity, specificity to its complementary strands and property of not being recognized at all by DNA polymerase as primer.
PNAClamp™ technology can be easily applied to detect only the mutated DNA sequences from the mixture with the wild type DNA sequences by PCR amplification. The wild type DNA fragments cannot be amplified by the PNA probes that are tightly bound, whereas only the mutated DNA sequences can be amplified selectively by PCR amplification.
The available products are EGFR, KRAS, NRAS, BRAF, PIK3CA, IDH1, IDH2, c-KIT, JAK2, BCR-ABL and TERT.
PNAClamp™ technology can be easily applied to detect only the mutated DNA sequences from the mixture with the wild type DNA sequences by PCR amplification. The wild type DNA fragments cannot be amplified by the PNA probes that are tightly bound, whereas only the mutated DNA sequences can be amplified selectively by PCR amplification.
The available products are EGFR, KRAS, NRAS, BRAF, PIK3CA, IDH1, IDH2, c-KIT, JAK2, BCR-ABL and TERT.
Product category: DNA testing, Polymerase chain reaction (PCR), Other molecular diagnostics testing
PANA qPCR™
PANA qPCR™ technology uses a sequence-specific PNA probe with a fluorescent reporter and quencher. The PNA probe is designed to hybridize specifically to a nucleotide region of the target sequence.
In the absence of target, no fluorescence is detected from the reporter due to its physical proximity to the quencher. During the annealing step, the PNA probe binds to its specific target sequence, separating the reporter and quencher such that the reporter is no longer quenched. Unlike TaqMan assays, PNA probe is not hydrolyzed during amplification because its resistant to enzyme degradation. PANA qPCR™ is a powerful tool for multiplexing, allelic discrimination experiments and quantitative analysis with high specificity and sensitivity.
In the absence of target, no fluorescence is detected from the reporter due to its physical proximity to the quencher. During the annealing step, the PNA probe binds to its specific target sequence, separating the reporter and quencher such that the reporter is no longer quenched. Unlike TaqMan assays, PNA probe is not hydrolyzed during amplification because its resistant to enzyme degradation. PANA qPCR™ is a powerful tool for multiplexing, allelic discrimination experiments and quantitative analysis with high specificity and sensitivity.
Product category: DNA testing, Polymerase chain reaction (PCR), Other molecular diagnostics testing
PANAMAX™ 48
PANAMAX™ 48 is an automated nucleic acid extraction system to extract maximum of 48 DNA/RNA from the samples at a run.
The solution is capable of suing large sample volume (up to 5ml without any structural changes).
It can extract various type of samples: Whole blood, Plasma, Cultured cells, BAL, Urine, Swab, FFPE tissue.
The extraction time is 25 to 35 minutes. (90 minutes for Plasma samples)
It has 10.1 inch touch screen for direct interaction with user with easy UI/UX.
Anti contamination (UV sanitation system) is built-in option and with firmware upgrade capability, regular maintenance and upgrade are covered.
The solution is capable of suing large sample volume (up to 5ml without any structural changes).
It can extract various type of samples: Whole blood, Plasma, Cultured cells, BAL, Urine, Swab, FFPE tissue.
The extraction time is 25 to 35 minutes. (90 minutes for Plasma samples)
It has 10.1 inch touch screen for direct interaction with user with easy UI/UX.
Anti contamination (UV sanitation system) is built-in option and with firmware upgrade capability, regular maintenance and upgrade are covered.
About us
Company portrait
PANAGENE will always make its best efforts to develop innovative platform technologies and strive to be a global leader in the field of molecular diagnostics.
We, PANAGENE Inc. have been developing and launching accurate and convenient in vitro diagnostic products consistently from Oncology to Infectious Diseases. We exercise strict quality management policy and make efforts to meet global standards and appropriate regulations for our IVD products.
PANAGENE has expertise especially in cancer-related molecular diagnostics including companion diagnostics using tissue or liquid biopsy. Our advanced technology provides not only high level of detection but also simple and convenient procedure to be used easily in the front-line hospitals and clinical laboratories.
(EGFR, KRAS, NRAS, BRAF, PIK3CA, IDH1, IDH2, JAK2, BCR-ABL, c-KIT, TERT, EML4-ALK, ROS1)
Also we apply our platform technology to maximize multiplex capability to detect using melting curve analysis with high-level performance.
(HPV, STD, CRE, TB/NTM)
Lastly, we have our automation extraction system to use with molecular diagnostics kits to provide full package solution for the user. The extraction machine is 100% in house developed and optimized with our kits. During this Pandemic, we are providing the machines and extraction kits to reach out who needs the testings.
(Viral, FFPE, cfDNA extraction kits)
PANAGENE is pursuing open innovation and seeking opportunity for collaboration with various organizations including pharmaceutical and diagnostics companies. We always welcome organizations who are interest in our technologies and/or products.
We will do our best for customer satisfaction and for realizing our vision, “Platform Technology Provider”.
We, PANAGENE Inc. have been developing and launching accurate and convenient in vitro diagnostic products consistently from Oncology to Infectious Diseases. We exercise strict quality management policy and make efforts to meet global standards and appropriate regulations for our IVD products.
PANAGENE has expertise especially in cancer-related molecular diagnostics including companion diagnostics using tissue or liquid biopsy. Our advanced technology provides not only high level of detection but also simple and convenient procedure to be used easily in the front-line hospitals and clinical laboratories.
(EGFR, KRAS, NRAS, BRAF, PIK3CA, IDH1, IDH2, JAK2, BCR-ABL, c-KIT, TERT, EML4-ALK, ROS1)
Also we apply our platform technology to maximize multiplex capability to detect using melting curve analysis with high-level performance.
(HPV, STD, CRE, TB/NTM)
Lastly, we have our automation extraction system to use with molecular diagnostics kits to provide full package solution for the user. The extraction machine is 100% in house developed and optimized with our kits. During this Pandemic, we are providing the machines and extraction kits to reach out who needs the testings.
(Viral, FFPE, cfDNA extraction kits)
PANAGENE is pursuing open innovation and seeking opportunity for collaboration with various organizations including pharmaceutical and diagnostics companies. We always welcome organizations who are interest in our technologies and/or products.
We will do our best for customer satisfaction and for realizing our vision, “Platform Technology Provider”.
Company data
Number of employees
50-99
Foundation
2001
Area of business
- Laboratory equipment
- Diagnostics
